https://www.nfljerseyshopdiscount.com You can unsubscribe at any time.Thank you for subscribingWe have more newslettersShow meSee ourprivacy noticeProfessor Andrew Pollard, head of the Oxford Vaccine Group, said: “The clinical studies are progressing very well and we are now initiating studies to evaluate how well the vaccine induces immune responses in older adults, and to test whether it can provide protection in the wider population.”We are very grateful to the huge support of the trial volunteers in helping test whether this new vaccine could protect humans against the pandemic coronavirus.”Here’s everything you need to know about Phase 2 of the vaccine trial, including who it involves and what it means for you.Who is involved in Phase 2? Phase 2 of the study involves expanding the age range of people the vaccine is assessed in, to include a small number of older adults and children. Aged over 70 Aged between 5 12 yearsWhat happens in Phase 2? The scientists will now assess the immune response to the vaccine in people of different ages.This will allow them to understand if there is variation i nn how well the immune system responds in older people or children.Participants will be randomised to receive one or two doses of either the coronavirus vaccine or a licensed vaccine (MenACWY) that will be used as a ‘control’ for comparison.The researchers explained: “The MenACWY vaccine is being used as an ‘active control’ vaccine in this study, to help us understand participants’ response to ChAdOx1 nCoV 19.Coronavirus vaccine trial extended to include children and older adults”The reason for using this vaccine, rather than a saline control, is because we expect to see some minor side effects from the ChAdOx1 nCOV 19 vaccine such as a sore arm, headache and fever. Saline does not cause any of these side effects.”If participants were to receive only this vaccine or a saline control, and went on to develop side effects, they would be aware that they had received the new vaccine.”It is critical for this study that participants remain blinded to whether or not they have received the vaccine, as, if they knew, this could affect their health behaviour in the community following vaccination, and may lead to a bias in the results of the study.”What is the vaccine? The vaccine, called ChAdOx1 nCoV 19, is made from a virus ChAdOx1, which is a weakened version of a common cold virus that causes infections in chimpanzees, that has been genetically changed so that it is possible to grow in humans.The researchers explained: “By vaccinating with ChAdOx1 nCoV 19, we are hoping to make the body recognise and develop an immune response to the Spike protein that will help stop the SARS CoV 2 virus from entering human cells and therefore prevent infection.”New coronavirus symptom to look for as doctors warn neck pain may be linked to COVID 19What happens in Phase 3? The phase 3 part of the study involves assessing how the vaccine works in a large number of people over the age of 18.This group will allow assessment of how well the vaccine works to prevent people from becoming infected with COVID 19.When will results of the trial be available? Unfortunately, it remains unclear when the results of the trial will be available.The researchers explained: “How quickly we reach the numbers required will depend on the levels of virus transmission in the community.”If transmission remains high, we may get enough data in a couple of months to see if the vaccine works, but if transmission levels drop, this could take up to 6 months..
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